Scientific publications
 

2025

Latosinska A, Mina IK, Nguyen TMN, Golovko I, Keller F, Mayer G, Rossing P, Staessen JA, Delles C, Beige J, Glorieux G, Clark AL, Schanstra JP, Vlahou A, Peter K, Rychlík I, Ortiz A, Campbell A, Rupprecht H, Persson F, Mischak H, Siwy J. In silico prediction of optimal multifactorial intervention in chronic kidney disease. J Transl Med. 2025 Aug 21;23(1):943. doi: 10.1186/s12967-025-06977-3. PMID: 40842026; PMCID: PMC12372250.

https://pubmed.ncbi.nlm.nih.gov/40842026/


Devos H, Mina IK, Paradeisi F, Makridakis M, Tserga A, Mokou M, Zoidakis J, Mischak H, Vlahou A, Latosinska A, Roubelakis MG. A Naturally Occurring Urinary Collagen Type I Alpha 1-Derived Peptide Inhibits Collagen Type I-Induced Endothelial Cell Migration at Physiological Concentrations. Int J Mol Sci. 2025 Aug 2;26(15):7480. doi: 10.3390/ijms26157480. PMID: 40806611; PMCID: PMC12347341.

https://pubmed.ncbi.nlm.nih.gov/40806611/


Bartochowski P, Cortijo I, Bhargava S, Jover B, Raynaud F, Boukhaled JH, Lajoix AD, Jankowski V, Jankowski J, Cordaillat-Simmons M, Argilés À, Gayrard N, Duranton F, Laget J. Gut alterations in a chronic kidney disease rat model with diet-induced vascular calcification. FEBS Open Bio. 2025 Aug;15(8):1219-1231. doi: 10.1002/2211-5463.70043. Epub 2025 Jun 17. PMID: 40526091; PMCID: PMC12319703.

https://pubmed.ncbi.nlm.nih.gov/40526091/


Martin EM, Genovese F, Mischak H, Siwy J, Rupprecht H, Catanese L, Latosinska A. Association of Urinary Collagen Type III Degradation Product With Kidney Function and Fibrosis in Chronic Kidney Disease Patients. Proteomics. 2025 Jun;25(11-12):e202400354. doi: 10.1002/pmic.202400354. Epub 2025 Apr 10. PMID: 40211596; PMCID: PMC12205290.

https://pubmed.ncbi.nlm.nih.gov/40211596/


Martin EM, Chang J, González A, Genovese F. Circulating collagen type I fragments as specific biomarkers of cardiovascular outcome risk: Where are the opportunities? Matrix Biol. 2025 May;137:19-32. doi: 10.1016/j.matbio.2025.03.001. Epub 2025 Mar 2. PMID: 40037418; PMCID: PMC11986567.

https://pubmed.ncbi.nlm.nih.gov/40037418/

Lopes MB, Coletti R, Duranton F, Glorieux G, Jaimes Campos MA, Klein J, Ley M, Perco P, Sampri A, Tur-Sinai A. The Omics-Driven Machine Learning Path to Cost-Effective Precision Medicine in Chronic Kidney Disease. Proteomics. 2025 Jan 10:e202400108. doi: 10.1002/pmic.202400108. Epub ahead of print. PMID: 39790049.

https://pubmed.ncbi.nlm.nih.gov/39790049/

2024

Mina IK, Iglesias-Martinez LF, Ley M, Fillinger L, Perco P, Siwy J, Mischak H, Jankowski V. Investigation of the Urinary Peptidome to Unravel Collagen Degradation in Health and Kidney Disease. Proteomics. 2024 Dec 30:e202400279. doi: 10.1002/pmic.202400279. Epub ahead of print. PMID: 39740102.

https://pubmed.ncbi.nlm.nih.gov/39740102/

 Jaimes Campos MA, Kabić S, Latosinska A, Anicic E, Siwy J, Dragušica V, Rupprecht H, Catanese L, Keller F, Perco P, Gomez- Gomez E, Beige J, Vlahou A, Mischak H, Vukelić D, Križan T, Frantzi M. A synthetic data generation pipeline to reproducibly mirror high-resolution multi-variable peptidomics and real-patient clinical data. medRxiv 2024.10.30.24316342.

https://www.medrxiv.org/content/10.1101/2024.10.30.24316342v1

Frattini T, Devos H, Makridakis M, Roubelakis MG, Latosinska A, Mischak H, Schanstra JP, Vlahou A, Saulnier-Blache JS. Benefits and limits of decellularization on mass-spectrometry-based extracellular matrix proteome analysis of mouse kidney. Proteomics. 2024 Sep;24(17):e2400052. doi: 10.1002/pmic.202400052. Epub 2024 Jun 19. PMID: 38896836.

https://pubmed.ncbi.nlm.nih.gov/38896836/

2023

Jaimes Campos MA, Mavrogeorgis E, Latosinska A, Eder S, Buchwinkler L, Mischak H, Siwy J, Rossing P, Mayer G, Jankowski J. Urinary peptide analysis to predict the response to blood pressure medication. Nephrol Dial Transplant. 2023 Oct 31:gfad223. doi: 10.1093/ndt/gfad223. Epub ahead of print. PMID: 37930730. 

https://pubmed.ncbi.nlm.nih.gov/37930730/

Please take a moment to check out the related video as well!

https://www.youtube.com/watch?v=o27WHYCCbv4&t=3s

Mina IK, Mavrogeorgis E, Siwy J, Stojanov R, Mischak H, Latosinska A, Jankowski V. Multiple urinary peptides display distinct sex-specific distribution. Proteomics. 2023, 26:e2300227. doi: 10.1002/pmic.202300227. Epub ahead of print. PMID: 37750242.

https://pubmed.ncbi.nlm.nih.gov/37750242/

Keller F, Beige J, Siwy J, Mebazaa A, An D, Mischak H, Schanstra JP, Mokou M, Perco P, Staessen JA, Vlahou A, Latosinska A. Urinary peptides provide information about the risk of mortality across a spectrum of diseases and scenarios. J Transl Med. 2023, 21(1):663. doi: 10.1186/s12967-023-04508-6. PMID: 37741989; PMCID: PMC10518109.

https://pubmed.ncbi.nlm.nih.gov/37741989/4

Jaimes Campos MA, Andújar I, Keller F, Mayer G, Rossing P, Staessen JA, Delles C, Beige J, Glorieux G, Clark AL, Mullen W, Schanstra JP, Vlahou A, Rossing K, Peter K, Ortiz A, Campbell A, Persson F, Latosinska A, Mischak H, Siwy J, Jankowski J. Prognosis and Personalized In Silico Prediction of Treatment Efficacy in Cardiovascular and Chronic Kidney Disease: A Proof-of-Concept Study. Pharmaceuticals (Basel). 2023, 16(9):1298. doi: 10.3390/ph16091298. PMID: 37765106; PMCID: PMC10537115.

https://pubmed.ncbi.nlm.nih.gov/37765106/

Laget J, Cortijo I, Boukhaled JH, Muyor K, Duranton F, Jover B, Raynaud F, Lajoix AD, Argilés À, Gayrard N. Cafeteria Diet-Induced Obesity Worsens Experimental CKD. Nutrients. 2023, 15(15):3331. doi: 10.3390/nu15153331. PMID: 37571269; PMCID: PMC10421241.

https://pubmed.ncbi.nlm.nih.gov/37571269/

Devos H, Zoidakis J, Roubelakis MG, Latosinska A, Vlahou A. Reviewing the Regulators of COL1A1. Int J Mol Sci. 2023, 24(12):10004. doi: 10.3390/ijms241210004. PMID: 37373151; PMCID: PMC10298483.

https://pubmed.ncbi.nlm.nih.gov/37373151/